李富花,中国科学院海洋研究所研究员、博士生导师。长期从事无脊椎动物特别是虾类繁殖生物学、功能基因组学和遗传育种方面的科学探索、技术研发和成果转化,取得一系列创新性成果。现担任国际无脊椎动物繁殖与发育学会副理事长、国际生物科学联合会中国委员会委员、亚洲发育与比较免疫学会委员、甲壳动物学会副理事长、国家虾蟹产业技术体系病害防控功能实验室主任等职务。主持国家重点研发计划项目、国家自然科学基金重点项目、国家基金委国际(地区)合作项目及国家虾蟹产业技术体系岗位科学家项目等国家级科研项目20余项。近年来,以第一或通讯作者在Nature Communication、PLoS Biology等发表SCI收录论文80余篇;获国家发明专利授权20余项,国际PCT专利授权2项;培育虾类国审新品种3个;获得省部级奖励5项。
联系方式:0532-82898836,fhli@qdio.ac.cn
现主持科研项目:
1. 国家重点研发计划项目,重要养殖虾蟹类种质创制和健康苗种繁育(2018YFD0901300),2018.12-2022.12,主持,在研;
2. 国家自然科学基金重点项目,凡纳滨对虾抗副溶血弧菌性状的遗传基础及调控机制研究(31830100),2019.1-2023.12,主持,在研;
3. 国家自然科学基金委国际合作项目,十足目甲壳动物生殖过程的多重调控机制:性别决定和性别分化的分子桥梁(31861143047),2019.1-2021.12,主持,在研;
4. 国家虾蟹产业技术体系岗位科学家项目,药物靶位开发(CARS-48),2016.1-2020,12,主持,在研;
5. 中国科学院A类先导专项项目子课题,虾、贝增产培优品种的精准设计(XDA24030105), 2019.11- 2024.10, 主持,在研;
6. 国家自然科学基金面上项目,凡纳滨对虾重组激活基因RAGs的结构与功能研究(41776158),2018.1- 2021.12, 主持,在研。
10篇代表性论文:
1. Jianbo Yuan, Xiaojun Zhang*, Yi Gao, Xiaoxi Zhang, Chengzhang Liu, Jianhai Xiang, and Fuhua Li*. Adaptation and molecular evidence for convergence in decapod crustaceans to deep-sea hydrothermal vent environments. Molecular Ecology, 2020, 29:3954–3969.
2. Fei Liu#, Shihao Li#, Yang Yu, Mingzhe Sun, Jianhai Xiang, Fuhua Li*, 2020. Effects of ammonia stress on the hemocytes of the Pacific white shrimp Litopenaeus vannamei. Chemosphere 239, 124759.
3. Xiaojun Zhang#, Jianbo Yuan#, Yamin Sun#, Shihao Li#, Yi Gao#, Yang Yu#, Chengzhang Liu, Quanchao Wang, Xinjia Lv, Xiaoxi Zhang, Ka Yan Ma, Xiaobo Wang, Wenchao Lin, Long Wang, Xueli Zhu, Chengsong Zhang, Jiquan Zhang, Songjun Jin, Kuijie Yu, Jie Kong, Peng Xu, Jack Chen, Hongbin Zhang, Patrick Sorgeloos, Amir Sagi, Acacia Alcivar-Warren, Zhanjiang Liu, Lei Wang, Jue Ruan, Ka Hou Chu*, Bin Liu*, Fuhua Li* & Jianhai Xiang*, 2019. Penaeid shrimp genome provides insights into benthic adaptation and frequent molting. Nature Communications, 10:356.
4. Shihao Li, Xinjia Lv, Fuhua Li*, Jianhai Xiang, 2019. Characterization of a lymphoid organ specific anti-lipopolysaccharide factor from shrimp reveals structure-activity relationship of the LPS-binding domains. Frontiers in Immunology, 10: 872.
5. Qian Zhang#, Yang Yu#, Quanchao Wang, Fei Liu, Zheng Luo, Chengsong Zhang, Xiaojun Zhang, Hao Huang, Jianhai Xiang, Fuhua Li*, 2019. Identification of Single Nucleotide Polymorphisms Related to the Resistance Against Acute Hepatopancreatic Necrosis Disease in the Pacific White Shrimp Litopenaeus vannamei by Target Sequencing Approach. Front. Genet. 10:700.
6. Yang Yu#, Quanchao Wang#, Qian Zhang, Zheng Luo, Yue Wang, Xiaojun Zhang, Hao Huang, Jianhai Xiang, Fuhua Li*, 2019. Genome Scan for Genomic Regions and Genes Associated with Growth Trait in Pacific White Shrimp Litopeneaus vannamei. Marine Biotechnology, 21:374-383.
7. Chengsong Zhang, Fang Su, Shihao Li, Yang Yu, Jianhai Xiang, Jianguo Liu*, Fuhua Li*, 2018. Isolation and identification of the main carotenoid pigment from a new variety of the ridgetail white prawn Exopalaemon carinicauda. Food Chemistry, 269, 450–454.
8. Shihao Li#, Zhiwei Wang#, Fuhua Li*, Kuijie Yu, Jianhai Xiang, 2017. A Novel Vascular Endothelial Growth Factor Receptor Participates in White Spot Syndrome Virus Infection in Litopenaeus vannamei. Front. Immunol. 8:1457.
9. Fuhua Li, Jianhai Xiang, 2013. Recent advances in researches on the innate immunity of shrimp in China. Developmental and Comparative Immunology, 39: 11-26.
10.Fuhua Li, Jianhai Xiang, 2013. Signaling pathways regulating innate immune responses in shrimp. Fish and Shellfish Immunology, 34:973-980.