生物与医药
岳洋,男,副研究员,硕士生导师。研究方向为海洋药物与生物制品,主要聚焦海洋生物活性分子的发现、结构解析、作用机理与成药性研究,在利用人工智能(AI)技术、分子网络技术等辅助海洋功能性分子的高效发现以及机制解析方面做出创新性研究。目前承担国家自然科学基金、山东省自然科学基金等省部级以上科研项目6项,以第一作者、通讯作者在Int. J. Biol. Macromol.、Food Res. Int.、Chem.-Biol. Interact.等国际期刊发表SCI论文14篇(Q1区论文9篇);以第一发明人申请国家发明专利5件,已授权2件;获得海洋科学技术奖一等奖1项。现任《海洋科学》青年编委,同时担任Int. J. Biol. Macromol.、Food Res. Int.、Toxicol. Sci.、LWT等国际知名期刊的审稿专家。
一、研究领域  
海洋活性物质的结构、功能与成药性研究
海洋生物高值化利用技术研究
海洋药物与制品的研究与开发
二、招生专业及方向
1.学术型硕士:海洋生物学,海洋药物与制品方向;
2.专业型硕士:生物与医药,海洋生物工程方向。
三、研究室及联系方式
实验海洋生物学重点实验室
联系方式:yueyang@qdio.ac.cn
办公电话:0532-82898703
四、承担的主要科研项目
1. 国家自然科学基金青年基金,41906082,2020/01-2022/12,项目负责人;
2. 中国博士后科学基金面上项目(一等资助),2018M630805,2018/06-2020/06,项目负责人;
3. 山东省自然科学基金,ZR2019BD025,2019/07-2022/06,项目负责人;
4. 福建省区域发展项目,2020N3011,2020/08-2022/12,项目技术负责人; 
5. 福建省STS项目,2023T3034,2023/01-2025/12,项目技术负责人;
6. 国家自然科学基金面上项目,41776163,2018/01-2021/12,科研骨干;                           
五、研究成果及奖励 
海洋科学技术奖一等奖(2018年,排名4/7)
六、代表性论文及著作
1. Qishan Suo, Jing Wang, Ning Wu, Lihua Geng, Quanbin Zhang, and Yang Yue*. 2024. 'Discovery of a novel nanomolar angiotensin-I converting enzyme inhibitory peptide with unusual binding mechanisms derived from Chlorella pyrenoidosa', International Journal of Biological Macromolecules, 280: 135873.
2. Yuhong Ouyang,Yang Yue*, Ning Wu, Jing Wang, Lihua Geng, and Quanbin Zhang*. 2024. 'Identification and anticoagulant mechanisms of novel factor XIa inhibitory peptides by virtual screening of a in silico generated deep-sea peptide database', Food Research International, 197: 115308.
3. Yang Yue, Huahua Yu*, Qishan Suo, Rongfeng Li, Song Liu, Ronge Xing, Quanbin Zhang, Pengcheng Li. Discovery of a novel jellyfish venom metalloproteinase inhibitor from secondary metabolites isolated from jellyfish-derived fungus Aspergillus versicolor SmT07[J]. Chemico-Biological Interactions, 2022, 365: 110113. 
4. Qishan Suo, Yang Yue*, Jing Wang, Ning Wu, Lihua Geng, Quanbin Zhang*. Isolation, identification and in vivo antihypertensive effect of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from Spirulina protein hydrolysate[J]. Food & Function, 2022, 13(17): 9108-9118. 
5. Zhenzhen Deng, Jing Wang, Ning Wu, Lihua Geng, Quanbin Zhang, Yang Yue*. Co-activating the AMPK signaling axis by low molecular weight fucoidan LF2 and fucoxanthin improves the HFD-induced metabolic syndrome in mice[J]. Journal of Functional Foods, 2022, 94: 105119. 
6. Yang Yue, Huahua Yu*, Rongfeng Li, Pengcheng Li*, 2021. Topical exposure to Nemopilema nomurai venom triggers oedematogenic effects: enzymatic contribution and identification of venom metalloproteinase. Toxins,13(1). 
7. Yang Yue, Quanbin Zhang*, Jing Wang, 2019. Integrated gas chromatograph-mass spectrometry (GC/MS) and MS/MS-based molecular networking reveals the analgesic and anti-inflammatory phenotypes of the sea slater Ligia exotica. Marine Drugs,17(7): 395. 
8. Yang Yue, Huahua Yu*, Rongfeng Li, Ronge Xing, Song Liu, Pengcheng Li*, 2019. Insights into individual variations in nematocyst venoms from the giant jellyfish Nemopilema nomurai in the Yellow Sea. Scientific Reports, 9(1): 3361. 
9. Yang Yue, Huahua Yu*, Rongfeng Li, Ronge Xing, Song Liu, Kecheng Li, Xueqin Wang, Xiaolin Chen, Pengcheng Li*, 2017. Functional elucidation of Nemopilema nomurai and Cyanea nozakii nematocyst venoms’ lytic activity using mass spectrometry and zymography. Toxins, 9, 47; doi:10.3390/toxins9020047. 
10. Yang Yue, Huahua Yu* , Rongfeng Li, Ronge Xing, Song Liu, Kecheng Li, Xueqin Wang, Xiaolin Chen, Pengcheng Li*, 2017. Biochemical and kinetic evaluation of the enzymatic toxins from two stinging scyphozoans Nemopilema nomurai and Cyanea nozakii. Toxicon, 125, 1-12.