生物与医药
 王雪芹理学博士,副研究员,硕士生导师。主要从事海洋生物活性肽的研究,即从鱼类、贝类等海洋生物资源中提取功能活性物质,研究其功效因子和序列结构,开发海洋功能食品与医用制品等。近年来主持国家自然科学基金、山东省自然科学基金、山东省新旧动能转换重大工程重大课题攻关项目、山东省重点研发计划项目(医用食品专项计划)、中科院STS计划项目等多项课题。目前已发表学术论文40余篇,获授权国家发明专利17余项,获省市部级奖项2项。

 一、研究领域  

海洋生物活性肽的结构功能 

海洋生物资源高值利用与功能制品的开发

二、招生专业及方向

生物与医药(海洋生物工程)

三、研究室及联系方式       

中国科学院实验海洋生物学重点实验室

联系方式:xueqinwang@qdio.ac.cn0532-82898702  

四、承担的主要科研项目

1. 国家自然科学基金(青年项目)鲐鱼肽对运动性疲劳致氧化应激和炎症反应的保护作用机制,2016-2018主持

2. 山东省重点研发计划项目(医用食品专项计划)牡蛎活性肽系列肝病全营养配方食品的研发及产业化,2017-2020100主持

3. 山东省新旧动能转换重大工程重大课题攻关项目海洋生物功能肽、鱼糜新制品和保水技术研发,2020-2022300 主持

4. 山东省自然科学基金面上项目:牡蛎活性肽特征序列的护肝作用及机制研究,2024-2026,主持。

五、研究成果及奖励         

1. 2019年海洋工程科学技术二等奖(第位)

2. 2016年青岛市科技进步一等奖(第位)                               

六、代表性论文及著作

1. Xueqin Wang, Huahua Yu, Ronge Xing, Song Liu, Xiaolin Chen, Pengcheng Li*. Structural properties, anti-fatigue and immunological effect of low molecular weight peptide from Monkfish. Journal of Functional Foods, 2023, 105: 105546.

2. Xueqin Wang, Huahua Yu, Ronge Xing, Pengcheng Li*. Hepatoprotective Effect of Oyster Peptide on Alcohol-Induced Liver Disease in Mice. International Journal of Molecular Sciences. 2022, 23, 8081.  

3. Xueqin Wang, Huahua Yu, Ronge Xing, Song Liu, Xiaolin Chen, Pengcheng Li*. Optimization of Oyster (Crassostrea talienwhanensis) Protein Hydrolysates Using Response Surface Methodology. Molecules. 2020, 25, (12):1-14. 

4. Xueqin Wang, Huahua Yu, Ronge Xing, Song Liu, Xiaolin Chen, Pengcheng Li*. Preparation and Identification of Antioxidative Peptides from Pacific Herring (Clupea pallasii) Protein. Molecules. 2019, 24, (10):1-17.  

5. Xueqin Wang, Huahua Yu, Ronge Xing, Song Liu, Xiaolin Chen, Pengcheng Li*. Effect and mechanism of oyster hydrolytic peptides on spatial learning and memory in mice. RSC Advances. 2018, 8 (11):6125-6135.  

6. Xueqin Wang, Huahua Yu, Ronge Xing, Xiaolin Chen, Rongfeng Li, Kecheng Li, Song Liu, Pengcheng Li*. Purification and identification of antioxidative peptides from mackerel (Pneumatophorus japonicus) protein. RSC Advances. 2018, 8, 20488-20498.

7. Xueqin Wang, Huahua Yu, Ronge Xing, Xiaolin Chen, Song Liu, Pengcheng Li*. Optimization of antioxidative peptides from mackerel (Pneumatophorus japonicus) viscera. Peer J. 2018, 6:e4373.

8. Xueqin Wang, Huahua Yu, Ronge Xing, Pengcheng Li*. Characterization, Preparation, and Purification of Marine Bioactive Peptides. BioMed Research International, 2017,1-16.  

9. Xueqin Wang, Huahua Yu, Ronge Xing, Xiaolin Chen, Song liu, Pengcheng Li*. Optimization of the Extraction and Stability of Antioxidative Peptides from Mackerel (Pneumatophorus japonicus) Protein. BioMed Research International, 2017, 1-14.

10. Wang Xueqin, Xing Ronge, Liu Song, Yu Huahua, Li Kecheng, Chen ZuoyuanLi Pengcheng. Purification and characterization of novelantioxidant peptides of different molecular weights from mackerel Pneumatophorus japonicus protein hydrolysate, Chinese Journal of Oceanology and Limnology, 2015, 33(1):159-168.

11. Xueqin Wang, Ronge Xing, Zuoyuan Chen, Huahua Yu, Rongfeng Li, Pengcheng Li. Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue, Food &Function, 2014, 5(9): 2113-2119.