生物与医药

李凌,女,理学博士,中国科学院海洋研究所研究员。2003年获中国海洋大学生物科学学士学位,2006年获中国海洋大学遗传学硕士学位,2009年获中国科学院海洋研究所海洋生物学博士学位。20092010年赴俄罗斯科学院基础生物问题研究所开展微藻光合产氢合作研究。主要从事能源微藻规模化培养、产能条件优化及其调控机制研究。目前已发表SCI论文40余篇,获得授权发明专利7项,主持了包括国家863计划项目、国家自然科学基金、国家海洋局海洋可再生能源专项等在内的项目7项,获省部级奖励1次。

一、研究领域 

1、能源微藻的大规模养殖

2、微藻产能(包括产油及产氢)机制研究

二、招生专业及方向

1、学术型硕士

海洋生物学-海洋生物天然产物及生物制品

海洋生物学-生理生化过程与调控

2、专业型硕士

生物与医药-海洋生物工程

三、研究室及联系方式      

研究室:实验海洋生物学重点实验室

邮箱:liling@qdio.ac.cn

电话:13553003836

四、承担的主要科研项目

1、主持青岛新能源山东省实验室开放课题海水小球藻-细菌共培养产氢增益机制及其应用基础研究100万元,2023.08-2025.08

2、主持国家自然科学基金面上项目原壳小球藻光合产氢及油脂积累的协同调控机制(32072945,直接经费58万元,2021.01-2024.12

3、主持国家自然科学基金面上项目海水小球藻缺氮光合产氢的分子基础及调控机制(41676142,直接经费66万元,2017.01-2020.12

4、主持国家自然科学基金青年项目绿藻的产氢代谢及其进化关系研究(31000114,经费22万元,2011.01-2013.12

5、主持国家海洋局海洋可再生能源专项支撑海洋能源微藻高效培养的敌害生物防治技术(GHME2011SW01,经费300万元,2011.08-2013.12

6、主持国家海洋局海洋可再生能源专项海洋微藻生物柴油规模化制备关键技术与装置的优化、耦联及应用研究(GHME2011SW03子课题产油海洋微藻规模化培养工艺流程的优化,经费40万元,2011.08-2013.12

7、主持国家863计划项目饵料型微藻新品系培育及饵料工程化高效生产技术,经费180万(2010AA10A403),2010.01-2010.11

五、研究成果及奖励

1、研究成果

构建了具有我国自主知识产权的能源微藻种质库及信息库;基于系统进化分析,发现微藻的油脂含量及产氢量与其系统进化地位具有一定的相关性,在此基础上筛选出油脂含量高、生长快、耐高温的海洋微藻,解决了能源微藻户外培养高温损伤的难题,为其大规模开发提供了条件。建立了缺氮诱导海洋微藻光合产氢新模式,解决了海水培养基无法缺硫的难题;阐明了海水小球藻在缺氮条件下的产氢机制。建立了海洋能源微藻培养的敌害生物综合防御方法和技术体系,构建了用于微藻规模培养的大型封闭式光生物反应器,实现了自动化数据采集和程序控制,有效提高培养成功率,降低生产成本,相关成果已在山东、江苏及云南多家企业应用,并获得了显著的经济效益。

2、奖励

2015年获海洋科学技术奖二等奖:用柱状光生物反应器生产微藻饵料与再生能源,第二完成人

六、代表性论文及著作

1. Ling Li; et al.; Photorespiration plays an important role in H2 production by marine Chlorella pyrenoidosa, Algal Research-Biomass Biofuels and Bioproducts, 2023,71:103072. (JCR一区)

2. Ling Li; et al.; Proteomic analysis of hydrogen production in Chlorella pyrenoidosa under nitrogen deprivation, Algal Research-Biomass Biofuels and Bioproducts, 2021, 53: 102143. (JCR一区)

3. Ling Li; et al.; Transcriptomic analysis of hydrogen photoproduction in Chlorella pyrenoidosa under nitrogen deprivation, Algal Research-Biomass Biofuels and Bioproducts, 2020, 47: 101827. (JCR一区)

4. Ling Li; et al.; Comparison of heat resistance and application potential of two lipid-rich Isochrysis galbana strains, Algal Research-Biomass Biofuels and Bioproducts, 2016, 20: 1-6. (JCR一区)

5. Ling Li; et al.; The enhancement of hydrogen photoproduction in marine Chlorella pyrerioidosa under nitrogen deprivation, International Journal of Hydrogen Energy, 2015, 40(43): 14784-14789. (JCR二区)

6. Ling Li; et al.; Screening and phylogenetic analysis of lipid-rich microalgae, Algal Research-Biomass Biofuels and Bioproducts, 2015, 11: 381-386. (JCR一区)

7. Ling Li; et al.; Genomic organization, polymorphisms and molecular evolution of the goose-type lysozyme gene from Zhikong scallop Chlamys farreri, Gene, 2013, 513(1):40-52.

8. Ling Li; et al.; First molluscan TNFR homologue in Zhikong scallop: molecular characterization and expression analysis, Fish & Shellfish Immunology, 2009, 27(5): 625–632. (JCR一区)

9. Ling Li; et al.; The polymorphism of lysozyme gene in Zhikong scallop (Chlamys farreri) and its association with susceptibility/resistance to Listonella anguillarum, Fish & Shellfish Immunology, 2009, 27(2):136-142. (JCR一区)

10. Litao Zhang; Ling Li; et al.; Enhanced biohydrogen and lipid coproduction in Chlorella protothecoides under nitrogen-limiting conditions in a closed system, Journal of Cleaner Production, 2022, 359:132169. (JCR一区)

11. Yongfu Li; Ling Li; et al.; Light absorption and growth response of Dunaliella under different light qualities, Journal of Applied Phycology, 2020, 32(2): 1041-1052. (JCR一区)

12. Evgeny Shastik; Ling Li; et al.; Some molecular aspects of hydrogen production by marine Chlorella pyrenoidosa under nitrogen deprivation condition in natural seawater, International Journal of Hydrogen Energy, 2020, 45(27): 13876-13883.JCR二区)

13. Evgeny Shastik; Ling Li; et al.; New methods for hydrogen production by marine microalga Chlorella pyrenoidosa in natural seawater, International Journal of Hydrogen Energy, 2019, 44: 14707-14714.JCR二区)

14. Litao Zhang; Ling Li; et al.; The role of photorespiration during H2 photoproduction in Chlorella protothecoides under nitrogen limitation, Plant Cell Reports, 2016, 35(1): 1-4.JCR一区)

15. Meilin He; Ling Li; et al.; Improvement of H2 photoproduction in Chlorella pyrenoidosa in artificial and natural seawater by addition of acetic acid and control of nutrients, Algal Research-Biomass Biofuels and Bioproducts, 2015, 10: 104-109.JCR一区)

16. Yuan Huang; Ling Li; et al.; Botanical pesticides as potential rotifer-control agents in microalgal mass culture. Algal Research-Biomass Biofuels and Bioproducts, 2014, 4: 62-69.JCR一区)

17. Litao Zhang; Ling Li; et al.; Comparison of the photosynthetic characteristics of two Isochrysis galbana strains under high light. Botanica Marina, 2014, 57(6): 477-481.JCR二区)

18. Pingping Song; Ling Li; et al.; Proteomic analysis in nitrogen-deprived Isochrysis galbana during lipid accumulation. PLoS One, 2013, 8(12): e82188.JCR一区)

19. Meilin He; Ling Li; et al.; Isolation of wild microalgae from natural water bodies for high hydrogen producing strains, International Journal of Hydrogen Energy, 2012, 37(5): 4046-4056.JCR一区)

20. Meilin He; Ling Li; et al.; The enhancement of hydrogen photoproduction in Chlorella protothecoides exposed to nitrogen limitation and sulfur deprivation. International Journal of Hydrogen Energy, 2012, 37(22): 16903-16915.JCR一区)