秦玉坤，男，博士，副研究员，硕士生导师。美国佐治亚大学复合糖研究中心博士后。主要从事农用海洋生物制品领域的研究与开发工作。针对我国农业绿色发展对新型农药产品的迫切需求以及当前安全高效农药严重匮乏的现状，以海洋甲壳资源中农用活性成分的挖掘与功能解析为核心研究目标，已构建形成“甲壳生物质废弃物→高值化学品”的可持续应用研发新模式。

一、研究领域  

1.海洋生物基农用化学品的化学与生物合成

2.自组装纳米农药的构筑与农业病害绿色防控

二、招生专业及方向

海洋生物学，海洋生物天然产物及生物制品方向

生物与医药，海洋生物工程方向   

三、研究室及联系方式       

研究室：实验海洋生物学重点实验室

联系方式：ykqin@qdio.ac.cn, 0532-82898707  

四、承担的主要科研项目

1.国家自然科学基金面上项目：基于pDOS策略的海洋甲壳源5-羟甲基糠醛衍生物的多样性合成及杀线活性评价(42076126),2021.1-2024.12，负责人

2.山东省重点研发计划（重大科技创新工程）课题：甲壳素源农用活性分子的先导优化技术及农用制品研发（2022CXGC020413），2022.10-2025.12，负责人

3.山东省自然科学基金面上项目：基于分子编辑策略的甲壳源活性前体化合物的先导优化与杀线活性研究（ZR2025MS456），2025.10-2028.9，负责人

4.青岛市科技惠民示范专项课题，基于定位修饰和活性耦合技术的壳聚糖复合物的制备、活性筛选及绿色增效防治剂开发（25-1-5-xdny-7-nsh），2025.3-2027.3，负责人

5.辽宁省自然科学基金-新农药创制与开发国家重点实验室联合开放基金：海洋生物源呋喃骨架结构化合物的多样性合成及杀线活性评价（2022-KF-25-03），2022.9-2024.8，负责人                                    

五、研究成果及奖励         

在甲壳多糖衍生化、甲壳寡糖/单糖缀合物合成、甲壳源平台化合物绿色转化及农用生物活性方向开展了系统性、深入性研究。以第一作者或通讯作者发表SCI论文30余篇，其中JCR一区论文22篇，ESI高被引论文1篇。以第一发明人申请/授权中国发明专利15项，主持制定团体标准1项，与企业联合申报获得农药登记证书5个，以第一完成人获得海洋工程科学技术奖与山东省海洋科技创新奖。

六、代表性论文及著作

1. Yukun Qin, Pengcheng Li*, Zhanyong Guo*. Cationic chitosan derivatives as potential antifungals: A review of structural optimization and applications. Carbohydrate Polymers, 2020, 236,116002.

2. Chengna Dong，Kun Gao, Yadong Song, Ronge Xing , Huahua Yu, Song Liu, Pengcheng Li, Yukun Qin*,A chloride-mediated low-energy pathway for selective 3A5AF production from N-acetylglucosamine via solubility-tailored catalysis, Molecular Catalysis,2025, 587: 115498

3. Linsong Wang, Kun Gao, Zhongwei Wang, Zhaoqian Fan, Yukun Qin*, 3‑Furoic Acid from Sea-Derived Aspergillus luchuensis Hy‑6 as a Valuable Lead Compound against Plant-Parasitic Nematodes in Cucumber, Journal of Agricultural and Food Chemistry, 2025, 73: 3468−3482

4. Linsong Wang, Zhaoqian Fan, Kun Gao, Yukun Qin*, Integration of transcriptomics and metabolomics of 2-furoic acid-treated Meloidogyne incognita reveals a calmodulin gene associated with motility and pathogenicity, Plant Physiology and Biochemistry, 2025, 220, 109480

5. Yadong Song, Kun Gao, Luxiao Zhou, Huahua Yu, Ronge Xing, Song Liu, Pengcheng Li,Yukun Qin*, Hydroxyapatite-loaded cobalt nanoparticles catalyze the 5-hydroxymethylfurfural green oxidation to 2,5-furandicarboxylic acid under mild conditions, Polyhedron, 2025, 273, 117490

6. Luxiao Zhou, Kun Gao, Huahua Yu, Ronge Xing, Song Liu, Weixiang Liu, Pengcheng Li, Yukun Qin*, Efficient conversion of chitin to 5-hydroxymethylfurfural in a formic acid/calcium chloride system, International Journal of Biological Macromolecules, 2024, 283: 137697

7. Luxiao Zhou, Kun Gao, Peng He*, Huahua Yu, Ronge Xing, Song Liu, Yukun Qin*, Efficient conversion of chitin to HMF under the cocatalytic system of formic acid and silicotungstic acid, Journal of Oceanology and Limnology, 2025: 43: 261–273

8. Zhaoqian Fan; Kun Gao; Linsong Wang; Yukun Qin*; Song Liu; Ronge Xing; Huahua Yu; Kecheng Li; Pengcheng Li*; Sulfonamide modified chitosan oligosaccharide with high nematicidal activity against Meloidogyne incognita, International Journal of Biological Macromolecules, 2024, 269: 132131

9. Linsong Wang; Yukun Qin*; Zhaoqian Fan; Kun Gao; Jiang Zhan; Ronge Xing; Song Liu; Pengcheng Li*; Novel Lead Compound Discovery from Aspergillus fumigatus 1T-2 against Meloidogyne incognita Based on a Chemical Ecology Study, Journal of Agricultural and Food Chemistry, 2022, 70(15): 4644-4657

10. Zhaoqian Fan; Linsong Wang; Yukun Qin*; Pengcheng Li*; Activity of chitin/chitosan/chitosan oligosaccharide against plant pathogenic nematodes and potential modes of application in agriculture: A review, Carbohydrate Polymers, 2023, 306: 120592