岳欣，女，副研究员，硕士生导师，美国加州理工学院访问学者。

主要从事海洋软体动物抗病机理及遗传选育研究。分别从流行病学、分子免疫学、遗传学系统研究了滩涂贝类发病机理和抗病机制，并作为骨干成员完成国审文蛤高产抗病新品种“科浙1号”、“科浙2号”的选育。在粘液免疫研究方面取得重大突破，首次发现文蛤能在粘液细胞中合成红霉素，打破了只有放线菌能合成红霉素的已有理论认知,提出了埋栖贝类适应环境与抵御微生物侵染的新策略。在PNAS、Scientific reports、Journal of Pathology等期刊发表论文20余篇，授权发明专利4项，代表性研究论文被Science期刊同步报道，并入选2022年度中国海洋与湖沼十大科技进展。

一、研究领域  

1、海洋软体动物抗病机理

2、贝类重要经济性状遗传解析与选育               

二、招生专业及方向

1、学术型硕士

海洋生物学，免疫学基础与应用方向；

海洋生物学，遗传学与遗传工程方向；

水产养殖，养殖遗传学与育种生物技术方向。

2、专业型硕士

生物与医药，海洋生物工程方向。

三、研究室及联系方式       

所在研究室：中国科学院实验海洋生物学重点实验室

邮箱：yuexin@qdio.ac.cn

电话：0532-82898863   

四、承担的主要科研项目

1、国家重点研发计划项目子课题，滩涂增养殖技术与生态农牧化新模式，2018.12-2022.12，主持。

2、山东省自然科学基金面上项目，MITF在文蛤深壳色—高抗病力关联中的作用研究，2021.1-2023.12，主持。

3、青岛海洋科学与技术国家实验室青年项目，MITF基因多效性在文蛤壳色-免疫关联中的作用研究，2018.11-2021.12，主持。

4、国家自然科学基金青年项目，酚氧化酶级联途径在文蛤壳色—免疫关联中的作用研究，2013.1-2015.12，主持。

5、现代农业产业技术体系，蛤蚶蛏种质资源与品种改良，2018.1-2025.12,主要参与。

五、研究成果及奖励

1、盐城市“黄海明珠”领军人才称号

2、浙江省科技进步二等奖，重要滩涂贝类良种培育技术体系创建与应用

3、2022年度中国海洋与湖沼十大科技进展

六、代表性论文及著作

1.Yue X, Zhang SJ, Wang HX, Yu JJ, Peng QC, Margaret M*, Liu BZ*. The mud-dwelling clam Meretrix petechialis secretes endogenously synthesized erythromycin. Proceedings of the National Academy of Sciences 2022, 119: e2214150119.

2.Yue X, Zhang SJ, Yu JJ, Liu BZ*. Identification of a laccase gene involved in shell periostracal tanning of the clam Meretrix petechialis. Aquatic Biology 2019, 28: 55–65.

3.Zhang SJ#, Yue X#, Yu JJ, Wang HX, Liu BZ. MITF regulates downstream genes in response to Vibrio parahaemolyticus infection in the clam Meretrix Petechialis. Frontiers in Immunology 2019, 10: 1547.

4.Zhang SJ, Yu JJ, Wang HX, Liu BZ, Yue X*. p38 MAPK is involved in the immune response to pathogenic Vibrio in the clam Meretrix petechialis. Fish and Shellfish Immunology 2019, 95: 456–463.

5.Yu JJ, Wang MX, Liu BZ, Yue X*, Li CL*. Gill symbionts of the cold-seep mussel Bathymodiolus platifrons: Composition, environmental dependency and immune control. Fish and Shellfish Immunology 2019, 86: 246–252.

6.Zhang SJ, Wang HX, Yu JJ, Jiang FJ, Yue X*, Liu BZ. Identification of a gene encoding microphthalmia-associated transcription factor and its association with shell color in the clam Meretrix petechialis. Comparative Biochemistry and Physiology, Part B 2018, 225: 75–83.

7.Yue X, Huan P, Hu YH, Liu BZ. Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus. Scientific Reports 2018, 8.

8.Yue X, Nie Q, Xiao GQ, Liu BZ*. Transcriptome analysis of shell-color related genes in the clam Meretrix meretrix. Marine Biotechnology 2015, 17: 364–374.

9.Yue X, Huan P, Xiao GQ, Liu BZ*. Expression patterns of an i-type lysozyme in the clam Meretrix meretrix along with larval development. Developmental & Comparative Immunology 2013, 41: 27–32.

10.Yue X, Wang HX, Huang XH, Wang C, Chai XL, Liu BZ*. Single nucleotide polymorphisms in i-type lysozyme gene and their correlation with vibrio-resistance and growth of clam Meretrix meretrix based on the selected resistance stocks. Fish & Shellfish Immunology 2012, 33: 559–568.

11.Yue X, Liu BZ*, Sun L. Isolation and characterization of a virulent Vibrio sp. bacterium from clams (Meretrix meretrix) with mass mortality. Journal of Invertebrate Pathology 2011, 106: 242–249.

12.Yue X, Liu BZ*, Xue QG. An i-type lysozyme from the Asiatic hard clam Meretrix meretrix potentially functioning in host immunity. Fish & Shellfish Immunology 2011, 30: 550–558.

13.Yue X, Liu BZ*, Sun L, Tang BJ. Cloning and characterization of a hsp70 gene from Asiatic hard clam Meretrix meretrix which is involved in the immune response against bacterial infection. Fish & Shellfish Immunology 2011, 30: 791–799.

14.Yue X, Liu BZ*, Xiang JH, Jia JT. Identification and characterization of the pathogenic effect of a Vibrio parahaemolyticus-related bacterium isolated from clam Meretrix meretrix with mass mortality. Journal of Invertebrate Pathology 2010, 103: 109–115.