一、研究领域
1.海洋生物发育机制及演化意义
2.典型性状的遗传基础及
3.软体动物基因编辑技术及应用
二、招生专业及方向
1. 博士及学术型硕士:
海洋生物学,繁殖、发育与调控技术方向
海洋生物学,遗传学与遗传工程方向
水产养殖,养殖遗传学与育种生物技术方向
2. 专业型硕士:
生物与医药,海洋生物工程方向
三、研究室及联系方式
研究室:实验海洋生物学重点实验室
邮箱:huanpin@qdio.ac.cn
电话:0532-82898863
四、承担的主要科研项目
1、国家自然科学基金面上项目,皱纹盘鲍酪氨酸酶基因家族对贝壳性状的调控机制研究(32273128),2023/01-2026/12,54万元,主持,在研。
2、青岛海洋科学与技术试点国家实验室“十四五”重大项目课题,特征器官的发育调控与谱系溯源(2022QNLM050101-2),2022/5-2025/4,400万元,主持,在研。
3、国家重点研发计划项目课题,贝类生长与品质性状的分子基础和调控机理研究(2018YFD0900104),2018/12-2022/12,746万元,子课题负责人,在研。
4、山东省人才项目,2021/1-2025/12,50万元,主持,在研。
5、国家自然科学基金面上项目,小G蛋白cdc42及下游效应基因维持贝壳发育区细胞边界的机制研究(41776157),2018/01-2021/12,68万元,主持,已结题。
6、国家自然科学基金青年项目,酪氨酸酶及相关调控基因在长牡蛎幼虫Ⅰ期胚壳发生中的功能研究(31001102),2011/01-2013/12,19万元,主持,已结题。
7、中国科学院青年创新促进会人才项目,2018/01-2021/12,80万元,主持,已结题。
8、中国科学院海洋研究所“汇泉青年学者”人才项目,2018/01-2020/12,50万元,主持,已结题。
五、代表性论文及著作
1.Huan, P.#, Wang, Q.#, Tan, S., & Liu, B. (2020). Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs. PNAS, 117(1), 503–512. (F1000Prime Recommended)
2.Tan, S.#, Huan, P.#, & Liu, B. (2022). Molluskan Dorsal–Ventral Patterning Relying on BMP2/4 and Chordin Provides Insights into Spiralian Development and Evolution. Molecular Biology and Evolution, 39(1), 1–18.
3.Wang, S.#, Zhang, J.#, Jiao, W.#, Li, J.#, Xun, X.#, Sun, Y.# Guo, X.#, Huan, P.# et al. (2017). Scallop genome provides insights into evolution of bilaterian karyotype and development. Nature Ecology & Evolution, 1(5), 0120. (封面论文)
4.Liu, X.#, Huan, P.#, & Liu, B. (2022). Nonmuscle Myosin II is Required for Larval Shell Formation in a Patellogastropod. Frontiers in Cell and Developmental Biology, 10(February), 1–11.
5.Sun, D., Huan, P., & Liu, B. (2022). Early mesodermal development in the patellogastropod Lottia goshimai. Evolutionary Applications, November 2021, 1–12.
6.Huan, P., Cui, M., Wang, Q., & Liu, B. (2021). CRISPR/Cas9-mediated mutagenesis reveals the roles of calaxin in gastropod larval cilia. Gene, 787, 145640.
7.Yang, W., Huan, P.*, & Liu, B. (2020). Early shell field morphogenesis of a patellogastropod mollusk predominantly relies on cell movement and F-actin dynamics. BMC Developmental Biology, 20(1), 18.
8.Liu, G., Huan, P., & Liu, B. (2020). Identification of three cell populations from the shell gland of a bivalve mollusc. Development Genes and Evolution, 230(1), 39–45.
9.Tan, S., Huan, P.*, & Liu, B. (2018). An investigation of oyster TGF-β receptor genes and their potential roles in early molluscan development. Gene, 663, 65–71.
10.Liu, G., Huan, P.*, & Liu, B. (2017). A SoxC gene related to larval shell development and co-expression analysis of different shell formation genes in early larvae of oyster. Development Genes and Evolution, 227(3), 181–188.
11.Tan, S., Huan, P., & Liu, B. (2017). Expression patterns indicate that BMP2/4 and Chordin, not BMP5-8 and Gremlin, mediate dorsal–ventral patterning in the mollusk Crassostrea gigas. Development Genes and Evolution, 227(2), 75–84.
12.Huan, P., Wang, H., & Liu, B. (2016). Assessment of housekeeping genes as internal references in quantitative expression analysis during early development of oyster. Genes & Genetic Systems, 91(5), 257–265.
13.Huan, P., Wang, H., & Liu, B. (2015). A label-free proteomic analysis on competent larvae and juveniles of the Pacific oyster Crassostrea gigas. PLoS One, 10(8), e0135008.
14.Wang, X., Liu, B., Liu, F., & Huan, P.* (2015). A calaxin gene in the Pacific oyster Crassostrea gigas and its potential roles in cilia. Zoological Science, 32(5), 419–426.
15.Liu, G., Huan, P., & Liu, B. (2015). A GATA2/3 gene potentially involved in larval shell formation of the Pacific oyster Crassostrea gigas. Development Genes and Evolution, 225(4), 253–257.
16.Huan, P., Liu, G., Wang, H., & Liu, B. (2014). Multiple ferritin subunit genes of the Pacific oyster Crassostrea gigas and their distinct expression patterns during early development. Gene, 546(1), 80–88.
17.Huan, P., Liu, G., Wang, H., & Liu, B. (2013). Identification of a tyrosinase gene potentially involved in early larval shell biogenesis of the Pacific oyster Crassostrea gigas. Development Genes and Evolution, 223(6), 389–394.
18.Huan, P., Wang, H., Dong, B., & Liu, B. (2012). Identification of differentially expressed proteins involved in the early larval development of the Pacific oyster Crassostrea gigas. Journal of Proteomics, 75(13), 3855–3865.
19.Huan, P., Wang, H., & Liu, B. (2012). Transcriptomic Analysis of the Clam Meretrix meretrix on Different Larval Stages. Marine Biotechnology, 14(1), 69–78.