一、研究领域
主要从事海洋生物群体基因组学研究,包括:群体遗传结构和本地适应性遗传机制解析,适应性演化机制探讨,性别决定遗传机制及性染色体演化机制研究,群体基因组学分析相关软件开发等。
二、招生专业及方向
海洋生态学,生物资源生态学方向
三、研究室及联系方式
海洋生态与环境科学重点实验室
邮箱:lyl@qdio.ac.cn
电话:0532-82898894
四、承担的主要科研项目
1、国家自然科学基金面上项目,基于全基因组测序的银鱼科鱼类性别决定和性染色体演化遗传机制研究,主持
2、国家自然科学基金青年科学基金项目,基于群体基因组学的中国沿海黑鲷群体遗传变异格局与本地适应性进化研究,主持
3、青岛市博士后研究人员应用研究项目资助,黑鲷中国南北地理群体遗传分化与本地适应性研究,主持
4、青岛海洋科学与技术试点国家实验室海洋生态与环境科学功能实验室青年人才培育项目,中国渤、黄海黑鲷群体基因组学研究,主持
五、研究成果及奖励
近些年围绕海洋生物基因组遗传标记资源开发,群体遗传结构和本地适应性解析,性别决定遗传机制探讨,群体基因组学分析相关软件开发等方面取得了一系列的研究成果。基于群体遗传学和基因组学技术解析了我国多种重要海洋鱼类如松江鲈、小黄鱼等的遗传资源现状、群体遗传结构及本地适应性遗传学机制;解析了大银鱼和松江鲈性别决定系统、性别决定遗传机制;查明了刀鲚适应淡水的平行演化机制;开发了多个群体基因组学数据分析软件如StructureSelector (https://lmme.ac.cn/StructureSelector)、RADassembler (https://github.com/lyl8086/RADscripts/tree/master/RADassembler)等,已被全球90多个国家的科研人员使用,总访问量逾17万次。
六、代表性论文及著作
1、Wang, Yixin; Yang, Yujia; Li, Yulong; Chen, Muyan, Identification of sex determination locus in sea cucumber Apostichopus japonicus using genome-wide association study, BMC Genomics, 2022, 23: 391.
2、Zong, Shao-Bing #; Li, Yu-Long #; Liu, Jin-Xian, Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish, Molecular Biology and Evolution, 2021, 38(4): 1317-1329.
3、Xing, Teng-Fei; Li, Yu-Long *; Liu, Jin-Xian, Female-specific genomic regions and molecular sex identification of the clearhead icefish (Protosalanx hyalocranius), BMC Genomics, 2021, 22: 495.
4、Li, Yu-Long; Xing, Teng-Fei; Liu, Jin-Xian, Genome-wide association analyses based on whole-genome sequencing of Protosalanx hyalocranius provide insights into sex determination of Salangid fishes, Molecular Ecology Resources, 2020, 20(4): 1038-1049.
5、Li, Yu-Long #; Xue, Dong-Xiu #; Zhang, Bai-Dong; Liu, Jin-Xian, Population Genomic Signatures of Genetic Structure and Environmental Selection in the Catadromous Roughskin Sculpin Trachidermus fasciatus, Genome Biology and Evolution, 2019, 11(7): 1751-1764.
6、Li, Yu-Long; Liu, Jin-Xian, StructureSelector: A web-based software to select and visualize the optimal number of clusters using multiple methods, Molecular Ecology Resources, 2018, 18(1): 176-177. (ESI高被引)
7、Li, Yu-Long; Xue, Dong-Xiu; Zhang, Bai-Dong; Liu, Jin-Xian, An optimized approach for local de novo assembly of overlapping paired-end RAD reads from multiple individuals, Royal Society Open Science, 2018, 5(2): 171589.
8、Xue, Dong-Xiu #; Li, Yu-Long #; Liu, Jin-Xian, A rapid and cost-effective approach for the development of polymorphic microsatellites in non-model species using paired-end RAD sequencing, Molecular Genetics and Genomics, 2017, 292(5): 1165-1174.
9、Li, Yu-Long; Xue, Dong-Xiu; Gao, Tian-Xiang; Liu, Jin-Xian, Genetic diversity and population structure of the roughskin sculpin (Trachidermus fasciatus Heckel) inferred from microsatellite analyses: implications for its conservation and management, Conservation Genetics, 2016, 17(4): 921-930.
10、Zhang, Bai-Dong; Li, Yu-Long; Xue, Dong-Xiu; Liu, Jin-Xian, Population genomic evidence for high genetic connectivity among populations of small yellow croaker (Larimichthys polyactis) in inshore waters of China, Fisheries Research, 2020, 225: 105505.
11、Cheng, Jiao; Hui, Min; Li, Yulong; Sha, Zhongli, Genomic evidence of population genetic differentiation in deep-sea squat lobster Shinkaia crosnieri (crustacea: Decapoda: Anomura) from Northwestern Pacific hydrothermal vent and cold seep, Deep Sea Research Part I: Oceanographic Research Papers, 2020, 156: 103188.