李才文，博士、研究员、博士生导师。2007年博士毕业于美国威廉玛丽学院(The College of William & Mary, USA), 后于美国弗吉尼亚海洋研究所(Virginia Institute of Marine Sciences, USA)从事博士后研究。2011年8月起，任中国科学院海洋研究所海洋生态与环境科学重点实验室责任研究员，入选中国科学院“BR计划”（A类）；2015年7月起，任院级重点实验室副主任。

致力于海洋寄生甲藻生物生态学研究，以影响海洋生物健康和具有重要生态功能的两类代表性海洋寄生甲藻--血卵涡鞭虫、阿米巴藻为主要研究对象，先后建立了其实验室连续培养体系，系统揭示了其生活史特征、生物多样性、传播扩散机理及其病原-宿主互作机制，完善了对于海洋寄生甲藻的科学认知，拓展了我国海洋甲藻研究的新领域。先后主持国家自然科学基金4项（联合基金重点项目1项、面上项目2项、青年项目1项），参与科技部重点研发专项、基金委创新群体项目等11项，在本领域专业学术期刊发表论文60篇。

一、研究领域 

重点关注海洋环境与水生生物健康，围绕（1）浮游植物群落与碳汇过程、（2）赤潮生物环境适应及其遗传调控机制、（3）寄生甲藻（Hematodinium spp. 、Amoebophrya spp. 等）生物学特征和生态学功能等专题开展系统研究。

二、招生专业及方向

海洋生态学，海洋生态安全方向；环境科学，海洋环境生物学方向

三、研究室及联系方式

研究室：海洋生态与环境科学重点实验室

邮箱：cwli@qdio.ac.cn

电话/传真: 0532–82898995

四、承担的主要科研项目

近5年承担项目：

l 海水甲壳类寄生性甲藻血卵涡鞭虫的寄生生活策略研究，国家自然科学基金项目，2021.1-2023.12

l 海水甲壳类寄生性甲藻血卵涡鞭虫爆发机制与生态防控研究，国家自然科学基金项目，2020.1-2023.12

l 寄生性甲藻阿米巴藻在有害藻华消长过程中的作用机制研究，国家自然科学基金项目，2019.1-2022.12

l 我国海水甲壳类寄生性甲藻的完整生活史研究，国家自然科学基金项目，2017.1-2020.12

l 典型致灾赤潮形成的分子机理及调控网络，科技部重点研发计划子任务，2017.7-2020.12

l  “海洋生态与环境科学”，国家基金委-山东省联合基金项目子课题，2016.1-2019.12

五、研究成果及奖励

近年来在海洋寄生甲藻基础研究方面取得的主要学术成果概述如下：

1. 海洋寄生甲藻-血卵涡鞭虫（Hematodinium）：在国际上首次建立了感染蟹类寄生甲藻-血卵涡鞭虫的实验室连续培养体系，揭示了其完整生活史、多样性特征、传播扩散机制、病原-宿主互作机制，提出了其流行病生态防控对策。研究成果丰富和完善了对于海洋寄生甲藻生物学特征的科学认知，为渔业生产中防控寄生甲藻流行病提供了理论依据和技术支持。相关研究共发表学术论文24篇，收录于Harmful Algae、Parasitology、Protist、Diseases of Aquatic Organisms、Aquaculture等本领域专业学术期刊。

2. 海洋寄生甲藻-阿米巴藻（Amoebophrya）：在国内率先开展了感染浮游生物寄生甲藻-阿米巴藻的系统研究，揭示了其宿主类群、多样性和时空分布特征，刻画了其完整生活史，解析了该寄生甲藻与其宿主甲藻的互作机制，明确了其特异性感染对于甲藻赤潮发生、发展的影响。相关研究拓展了我国海洋甲藻研究的新领域，为进一步揭示其生态学功能奠定了基础。以上成果共发表学术论文17篇，收录于Harmful Algae、Marine biology、Journal of Eukaryotic Microbiology、ECSS等本领域专业学术期刊。 

六、代表性论文及著作

近五年主要研究论文：

1.Sha Xu; Cheng He; Zhenjun Kang; Shuqun Song; Caiwen Li*. The ecological responses of bacterioplankton during a Phaeocystis globosa bloom in Beibu Gulf, China highlighted by integrated metagenomics and metatranscriptomics. Marine Biology, 2022, 169:36.

2.Cheng He; Sha Xu; Shuqun Song; Caiwen Li*. Spatial and diel variations of the prokaryotic community in the Phaeocystis globosa blooms area of Beibu Gulf. Acta Oceanologica Sinica, 2022. (DOI: 10.1007/s13131-022-1984-6).

3.Meng Li; Qian Huang; Xiaoyang Lv; Hamish J. Small; Caiwen Li*. Integrative omics analysis highlights the immunomodulatory effects of the parasitic dinoflagellate Hematodinium on crustacean hemocytes. Fish and Shellfish Immunology, 2022, 125: 35-47.

4.Tiantian Chen, Yingxin Zhang, Shuqun Song, Yun Liu, Xiaoxia Sun, Caiwen Li*. Diversity and seasonal variation of marine phytoplankton in Jiaozhou Bay, China revealed by morphological observation and metabarcoding. Journal of Oceanology and Limnology, 2022, 40 (2): 577-591.

5.Caiwen Li*; Meng Li; Qian Huang. The parasitic dinoflagellate Hematodinium infects marine custaceans, Marine Life Science & Technology, 2021, 3: 313-325.

6.Tiantian Chen; Yun Liu; Zhangxi Hu; Shuqun Song; Caiwen Li*. Chloroplast Ultrastructure and Photosynthetic Response of the Dinoflagellate Akashiwo sanguinea Throughout Infection by Amoebophrya sp. Front. Mar. Sci. 2021, 8:742498. doi: 10.3389/fmars.2021.742498.

7.Tiantian Chen; Yingxin Zhang; Shuqun Song; Yun Liu; Xiaoxia Sun; Caiwen Li*. Diversity and seasonal variation of marine phytoplankton in Jiaozhou Bay, China revealed by morphological observation and metabarcoding. Journal of Oceanology and Limnology, 2021. https://doi.org/10.1007/s00343-021-0457-7.

8.Meng Li; Qian Huang; Xiaoyang Lv; Shuqun Song; Caiwen Li*. The parasitic dinoflagellate Hematodinium infects multiple crustaceans in the polyculture systems of Shandong Province, China, Journal of Invertebrate Pathology, 2021, 178: 107523.

9.Qian Huang; Meng Li; Fei Wang; Shuqun Song; Caiwen Li*. Transmission pattern of the parasitic dinoflagellate Hematodinium perezi in polyculture ponds of coastal China, Aquaculture, 2021, 538: 736549.

10.Cheng He; Sha Xu; Zhenjun Kang; Shuqun Song; Caiwen Li*. Prokaryotic community composition and structure during the Phaeocystis globosa bloom in the Beibu Gulf, China, Aquatic Microbial Ecology, 2021, 86: 137-151.

11.Sha Xu; Cheng He; Shuqun Song; Caiwen Li*. Spatialtemporal dynamics of marine microbial communities following a Phaeocystis bloom: biogeography and co-occurrence patterns, Environmental Microbiology Reports, 2021, 13(3): 294-308.

12.Yun Liu; Tiantian Chen; Xiaoting Wang; Shuqun Song; Caiwen Li*. Variation in the photosynthetic activities of the dinoflagellate Akashiwo sanguinea during formation of resting cysts, Marine Biology, 2020, 167: 158.

13.Tiantian Chen; Yun Liu; Sha Xu; Shuqun Song; Caiwen Li*. Variation of Amoebophrya community during bloom of Prorocentrum donhaiense Lu in coastal waters of the East China Sea, Estuarine, Coastal and Shelf Science, 2020, 243: 1-11.

14.Meng Li; Jinfeng Wang; Qian Huang; Caiwen Li*. Proteomic analysis highlights the immune responses of the hepatopancreas against Hematodinium infection in Portunus trituberculatus, Journal of Proteomics, 2019, 197: 92-105.

15.Qian Huang; Meng Li; Fei Wang; Caiwen Li*. The parasitic dinoflagellate Hematodinium perezi infecting mudflat crabs, Helice tientsinenses, in polyculutre system in China, Journal of Invertebrate Pathology, 2019, 166: 107229.

16.Yun Liu; Tiantian Chen; Shuqun Song; Caiwen Li*. Variation in biochemical composition during encystment of the planktonic dinoflagellate Akashiwo sanguinea in N-limited cultures, Marine Biology, 2019, 166: 120.

17.Tiantian Chen; Jie Xiao; Yun Liu; Shuqun Song; Caiwen Li*. Distribution and genetic diversity of the parasitic dinoflagellate Amoebophrya in coastal waters of China, Harmful Algae, 2019, 89, 101633.

18.贺成; 宋书群; 李才文*. 广西北部湾海域球形棕囊藻囊体时空分布及其影响因素, 海洋与湖沼, 2019, 50(3): 630-643.

19.贺成; 徐沙; 宋书群; 李才文*. 北部湾北部海域水体异养细菌的时空分布特征研究, 海洋学报, 2019, 41(4): 94-108.

20.刘云; 陈田田; 宋书群; 李才文*. 不同氮浓度条件下红色赤潮藻脂肪酸含量及组成特征, 海洋与湖沼, 2019, 50(2): 301-307.

21.李蒙; 王金凤; 黄骞; 李才文*. 三疣梭子蟹含硒谷胱甘肽过氧化物酶基因克隆及其表达分析, 海洋与湖沼, 2019, 50(1): 149-158.

22.陈田田; 宋书群; 刘云; 李才文*. 2015-2016年长江口及其邻近海域甲藻群落与阿米巴藻感染的周年变化, 海洋与湖沼, 2019, 50(1): 139-148.

23.Meng Li; Jinfeng Wang; Qian Huang; Caiwen Li*. Proteomic analysis highlights the immune responses of the hepatopancreas against Hematodinium infection in Portunus trituberculatus, Journal of Proteomics, 2019, 197: 92-105.

24.Meng Li; Qian Huang; Jinfeng Wang; Caiwen Li*. Different expression of microRNAs in Portunus trituberculatus in response to Hematodinium parasites, Fish and Shellfish Immunology, 2018, 83: 134-139.

25.Zhao Li; Shuqun Song; Caiwen Li*; Zhiming Yu. The sinking of the phytoplankton community and its contribution to seasonal hypoxia in the Changjiang (Yangtze River) estuary and its adjacent waters, Estuarine, Coastal and Shelf Science, 2018, 208:170-179.

26.Tiantian Chen; Yun Liu; Shuqun Song; Caiwen Li*. Characterization of the parasitic dinoflagellate Amoebophrya sp. infecting Akashiwo sanguinea in coastal waters of China, Journal of Eukaryotic Microbiology, 2018, 65, 448-457.

27.Shuqun Song; Zhao Li; Caiwen Li*; Zhiming Yu. The response of spring phytoplankton assemblage to diluted water and upwelling in the eutrophic Changjiang (Yangtze River) Estuary, Acta Oceanologica Sinica, 2017, 36(12): 101-110.

28.李照; 宋书群; 李才文*; 俞志明. 丰、枯水期长江口邻近海域浮游植物群落结构特征及其环境影响初探, 海洋学报, 2017, (10): 124-144.

29.Jinfeng Wang; Meng Li; Jie Xiao; Wenjun Xu; Caiwen Li*. Hematodinium spp. infections in wild and cultured populations of marine crustaceans along the coast of China, Diseases of aquatic organisms, 2017, 124: 181-191.

30.田达玮; 宋书群; 陈田田; 李照; 刘云; 梁俊华; 李才文*. 胶州湾夜光藻种群动态及其大量繁殖的生态机制, 海洋与湖沼, 2017, (02): 276-284.

31.Yun Liu; Shuqun Song; Tiantian Chen; Caiwen Li*. The diversity and structure of marine protists in the coastal waters of China revealed by morphological observation and 454 pyrosequencing, Estuarine Coastal And Shelf Science, 2017, 189: 143-155.

32.Caiwen Li*; Tiantian Chen. A novel hematoxylin and eosin stain assay for detection of the parasitic dinoflagellate Amoebophrya, Harmful Algae, 2017, 62: 30-36.